PRODUCTION OF PEG-MODIFIED BOVINE HEMOGLOBIN - ECONOMICS AND FEASIBILITY

被引：12

作者：

BRADLEY, R

SLOSHBERG, S

NHO, K

CZUBA, B

SZESKO, D

SHORR, R

机构：

[1] Enzon, Inc., Piscataway

来源：

ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY | 1994年 / 22卷 / 03期

关键词：

D O I：

10.3109/10731199409117896

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Bovine hemoglobin has many advantages as a blood substitute: a) it's ready availability; b) it's low cost; c) it's oxygen carrying capacity; and d) the ease with which it can be modified with polyethylene glycol (PEG) to improve its pharmacokinetic profile. This study investigates the potential of PEG-modified bovine hemoglobin as a cost-effective blood substitute.

引用

页码：657 / 667

页数：11