TONIC AND PHASIC BLOCK OF NEURONAL SODIUM CURRENTS BY 5-HYDROXYHEXANO-2',6'-XYLIDE, A NEUTRAL LIDOCAINE HOMOLOG

被引：23

作者：

CHERNOFF, DM

STRICHARTZ, GR

机构：

[1] BRIGHAM & WOMENS HOSP,HARVARD MIT DIV HLTH SCI & TECHNOL,ANESTHESIA RES LABS,BOSTON,MA 02115

[2] HARVARD UNIV,SCH MED,DEPT BIOL CHEM & MOLEC PHARMACOL,BOSTON,MA 02115

来源：

JOURNAL OF GENERAL PHYSIOLOGY | 1989年 / 93卷 / 06期

关键词：

D O I：

10.1085/jgp.93.6.1075

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

引用

页码：1075 / 1090

页数：16

共 35 条

[1] LOCAL-ANESTHETICS - EFFECTS ON PERMEABILITY PROPERTIES OF NODAL MEMBRANE IN MYELINATED NERVE-FIBERS FROM XENOPUS - POTENTIAL CLAMP EXPERIMENTS [J].

ARHEM, P ;

FRANKENHAEUSER, B .

ACTA PHYSIOLOGICA SCANDINAVICA, 1974, 91 (01) :11-21

[2] LIDOCAINE BLOCK OF CARDIAC SODIUM-CHANNELS [J].

BEAN, BP ;

COHEN, CJ ;

TSIEN, RW .

JOURNAL OF GENERAL PHYSIOLOGY, 1983, 81 (05) :613-642

[3] EVIDENCE FOR 2 TRANSIENT SODIUM CURRENTS IN THE FROG NODE OF RANVIER [J].

BENOIT, E ;

CORBIER, A ;

DUBOIS, JM .

JOURNAL OF PHYSIOLOGY-LONDON, 1985, 361 (APR) :339-360

[4] LIPID SOLUBILITY MODULATES PH POTENTIATION OF LOCAL-ANESTHETIC BLOCK OF VMAX REACTIVATION IN GUINEA-PIG MYOCARDIUM [J].

BROUGHTON, A ;

GRANT, AO ;

STARMER, CF ;

KLINGER, JK ;

STAMBLER, BS ;

STRAUSS, HC .

CIRCULATION RESEARCH, 1984, 55 (04) :513-523

[5]

CHERNOFF DM, 1988, BIOPHYS J, V53, pA537

[6]

COLQUAHOUN D, 1971, LECTURES BIOSTATISTI, P263

[7]

COURTNEY KR, 1975, J PHARMACOL EXP THER, V195, P225

[8]

COURTNEY KR, 1978, J PHARMACOL EXP THER, V207, P594

[9] MEMBRANE CURRENTS IN ISOLATED FROG NERVE FIBRE UNDER VOLTAGE CLAMP CONDITIONS [J].

DODGE, FA ;

FRANKENHAEUSER, B .

JOURNAL OF PHYSIOLOGY-LONDON, 1958, 143 (01) :76-90

[10]

FRAZIER DT, 1970, J PHARMACOL EXP THER, V171, P45

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