NEURITE OUTGROWTH ELICITED BY EMBRYONIC CHICK HEART - PARTIAL-PURIFICATION OF THE ACTIVE FACTOR

被引：53

作者：

EBENDAL, T ^{[1
]}

BELEW, M ^{[1
]}

JACOBSON, CO ^{[1
]}

PORATH, J ^{[1
]}

机构：

[1] UNIV UPPSALA,DEPT BIOCHEM,S-75123 UPPSALA,SWEDEN

来源：

NEUROSCIENCE LETTERS | 1979年 / 14卷 / 01期

关键词：

D O I：

10.1016/0304-3940(79)95350-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Chick heart explants stimulate a dense outgrowth of neurites in cocultured spinal, sympathetic and ciliary ganglia. A factor sharing these properties was partially purified by gel filtration of extract prepared from lyophilized 18-day embryonic hearts. The active factor has an apparent molecular weight of roughly 40,000 and is evidently distinct from nerve growth factor (NGF) by stimulating the parasympathetic ciliary neurons and by lack of cross-reactivity with antibodies to NGF. © 1979.

引用

页码：91 / 95

页数：5

共 14 条

[1] GEL-FILTRATION BEHAVIOUR OF PROTEINS RELATED TO THEIR MOLECULAR WEIGHTS OVER A WIDE RANGE
ANDREWS, P
[J]. BIOCHEMICAL JOURNAL, 1965, 96 (03) : 595 - &
[2] NERVE GROWTH-FACTOR
BRADSHAW, RA
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1978, 47 : 191 - 216
[3] INDUCTION OF NEURITE OUTGROWTH BY A CONDITIONED-MEDIUM FACTOR BOUND TO CULTURE SUBSTRATUM
COLLINS, F
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (10) : 5210 - 5213
[4] TESTS OF POSSIBLE ROLE OF NGF IN NEURITE OUTGROWTH STIMULATION EXERTED BY GLIAL CELLS AND HEART EXPLANTS IN CULTURE
EBENDAL, T
JACOBSON, CO
[J]. BRAIN RESEARCH, 1977, 131 (02) : 373 - 378
[5] TISSUE EXPLANTS AFFECTING EXTENSION AND ORIENTATION OF AXONS IN CULTURED CHICK-EMBRYO GANGLIA
EBENDAL, T
JACOBSON, CO
[J]. EXPERIMENTAL CELL RESEARCH, 1977, 105 (02) : 379 - 387
[6] EBENDAL T, 1978, FORM SHAPING MOVEMEN, V6, P235
[7] EBENDAL T, DEV BIOL
[8] TISSUE CULTURE ASSAY OF NERVE GROWTH FACTOR AND OF SPECIFIC ANTISERUM
FENTON, EL
[J]. EXPERIMENTAL CELL RESEARCH, 1970, 59 (03) : 383 - &
[9] NON-EQUIVALENCE OF CONDITIONED MEDIUM AND NERVE GROWTH-FACTOR FOR SYMPATHETIC, PARASYMPATHETIC, AND SENSORY NEURONS
HELFAND, SL
RIOPELLE, RJ
WESSELLS, NK
[J]. EXPERIMENTAL CELL RESEARCH, 1978, 113 (01) : 39 - 45
[10] NERVE GROWTH FACTOR
LEVIMONTALCINI, R
ANGELETTI, PU
[J]. PHYSIOLOGICAL REVIEWS, 1968, 48 (03) : 534 - +

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