CYTOKININ OF WHEAT GERM TRANSFER RNA - 6-(4-HYDROXY-3-METHYL-2-BUTENYLAMINO)-2-METHYLTHIO-9-BETA-D-RIBOFURANOSYLPURINE

被引:47
作者
HECHT, SM
LEONARD, NJ
BURROWS, WJ
ARMSTRONG, DJ
SKOOG, F
OCCOLOWITZ, J
机构
[1] Department of Chemistry and Chemical Engineering, University of Illinois, Urbana, IL
[2] Institute of Plant Development, University of Wisconsin, Madison, WI
[3] Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN
[4] Laboratory of Molecular Biology, University of Wisconsin, Madison, WI
关键词
D O I
10.1126/science.166.3910.1272
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A new modified nucleoside is responsible, in part, for the cytokinin activity of transfer RNA from wheat germ. The structure as judged by mass spectrometry is 6-(4-hydroxy-3-methyl-2-butenylamino)-2-methylthio-9-β-D- ribofuranosylpurine. Unequivocal synthesis afforded material having ultraviolet, mass spectral, and chromatographic properties identical with those of the natural product.
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页码:1272 / +
页数:1
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