AMIDES OF VEGETABLE ORIGIN .12. A NEW SERIES OF ALKA-2,4-DIENOIC TYRAMINE-AMIDES FROM ANACYCLUS PYRETHRUM DC (COMPOSITAE)

Anacyclus pyrethrum D.C. (Compositae) contains N-(2′-p-hydroxyphenylethyl) deca-, dodeca-, and tetradeca-trans-2, trans-4-dienamide, a new series of tyramine amides corresponding to isobutylamides which this plant produces. The tyramides, and the corresponding isobutylamides, are synthesised stereospecifically by phosphonate-anion synthesis. Anacyclus pyrethrum is found to contain the lignan (+)-sesamin and attention is drawn to the co-occurrence of lipid (and other) amides with lignans in a number of plants from three families (Compositae, Piper-aceae, and Ruaceae).