DISCRIMINATION OF STEROID-HORMONES BY NOVEL CAGE-TYPE AZACYCLOPHANES BEARING CHIRAL BINDING-SITES

被引：27

作者：

MURAKAMI, Y

HAYASHIDA, O

ITO, T

HISAEDA, Y

机构：

来源：

CHEMISTRY LETTERS | 1992年 / 03期

关键词：

D O I：

10.1246/cl.1992.497

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel cage-type azacyclophanes bearing chiral binding sites provided by L- and D-valine residues exhibited discrimination toward steroid hormones in D2O-CD3OD (3:1 v/v), as effected by hydrophobic and pi - pi interactions. In addition, chirality-based discrimination of alpha- and beta-estradiol was attributed to their different modes of hydrogen bonding with the hosts.

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页码：497 / 500

页数：4

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