NEW SYNTHESIS OF SUGAR, NUCLEOSIDE AND ALPHA-AMINO-ACID PHOSPHONATES

被引：36

作者：

BARTON, DHR

GERO, SD

QUICLETSIRE, B

SAMADI, M

机构：

[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE

[2] TEXAS A&M UNIV SYST,DEPT CHEM,COLLEGE STN,TX 77843

来源：

TETRAHEDRON | 1992年 / 48卷 / 09期

关键词：

PHOSPHONATES-THIOHYDROXAMIC ESTERS-RADICAL-DECARBOXYLATION-AZT;

D O I：

10.1016/S0040-4020(01)88721-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Photolysis of N-hydroxy-2-thiopyridone esters derived from uronic acids or alpha-amino acids in presence of vinyl phosphonate affords the corresponding phosphonate derivatives. A convenient route for the synthesis of the isostere of AZT-5' monophosphate is described.

引用

页码：1627 / 1636

页数：10

共 34 条

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[6] RADICAL-ADDITION TO VINYL PHOSPHONATES - A NEW SYNTHESIS OF ISOSTERIC PHOSPHONATES AND PHOSPHONATE ANALOGS OF ALPHA-AMINO-ACIDS
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