SAMPLE-SIZE FOR REPEATED-MEASURES STUDIES WITH BINARY RESPONSES

被引：20

作者：

LIPSITZ, SR ^{[1
]}

FITZMAURICE, GM ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,DANA FARBER CANC INST,DIV BIOSTAT & EPIDEMIOL,BOSTON,MA 02115

来源：

STATISTICS IN MEDICINE | 1994年 / 13卷 / 12期

关键词：

D O I：

10.1002/sim.4780131205

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We consider the sample size required for repeated measures studies when the response variable is binary. We propose the use of weighted least squares (WLS) for calculating the minimum sample size required to detect some minimum clinically important treatment effect. We provide tabulated values of the estimated sample sizes for a simple example and we discuss some practical considerations in determination of sample size with repeated binary responses.

引用

页码：1233 / 1239

页数：7

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