SIMPSON-GOLABI-BEHMEL SYNDROME - CONGENITAL DIAPHRAGMATIC-HERNIA AND RADIOLOGIC FINDINGS IN 2 PATIENTS AND FOLLOW-UP OF A PREVIOUSLY REPORTED CASE

This report suggests the association of congenital diaphragmatic hernia in Simpson. Golabi-Behmel syndrome by describing two unrelated males with this malformation. One male was the maternal half-nephew of our previously reported 8-year-old boy with this syndrome. Review of the skeletal roentgenograms of these 2 affected males, and those of the previously reported 8-year-old, documents flare of the iliac wings, narrow sacroiliac notches, and the presence of two carpal ossification centers as a newborn (''advanced bone age''). We also report the follow-up of the 8-year-old boy, now 16 years old, who continues to have significant overgrowth and speech, dental, developmental, and adjustment problems.