RETRACTED: IS KAPOSIS-SARCOMA-ASSOCIATED HERPESVIRUS DETECTABLE IN SEMEN OF HIV-INFECTED HOMOSEXUAL MEN (Retracted article. See vol. 351, pg. 1365, 1998)

被引：102

作者：

LIN, JC

LIN, SC

MAR, EC

PELLETT, PE

STAMEY, FR

STEWART, JA

SPIRA, TJ

机构：

[1] Centers for Disease Control and Prevention, GA30333, 1600 Clifton Road, MS-D10, Atlanta

来源：

LANCET | 1995年 / 346卷 / 8990期

关键词：

D O I：

10.1016/S0140-6736(95)91931-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We explored a possible route of transmission of Kaposi's sarcoma-associated herpes virus (KSHV) with nested and unnested PCR techniques. We looked for KSHV DNA sequences in semen of HIV-positive homosexual men and HIV-negative healthy semen donors. With unnested primers we found KSHV sequences in 21 of 33 (64%) homosexual men and in none of 30 healthy donors. With a nested PCR assay, 30 of 33 (91%) specimens from the homosexual men and 7 of 30 (23%) specimens from healthy donors had detectable KSHV sequences. Over 5 years of follow-up, 13 of 30 KSHV-positive homosexual men (43%) developed KS compared with none of the 3 KSHV-negative homosexual men.

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收藏

页码：1601 / 1602

页数：2

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