EVALUATION OF UNCERTAINTY IN INPUT PARAMETERS TO PHARMACOKINETIC MODELS AND THE RESULTING UNCERTAINTY IN OUTPUT

被引：54

作者：

FARRAR, D ^{[1
]}

ALLEN, B ^{[1
]}

CRUMP, K ^{[1
]}

SHIPP, A ^{[1
]}

机构：

[1] CLEMENT ASSOCIATES INC,1201 GAINES ST,RUSTON,LA 71270

来源：

TOXICOLOGY LETTERS | 1989年 / 49卷 / 2-3期

关键词：

D O I：

10.1016/0378-4274(89)90044-1

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

引用

页码：371 / 385

页数：15

共 14 条

[1]

ARMS A, 1986, REFERENCE PHYSL PARA

[2]

CASTER WO, 1956, P SOC EXP BIOL MED, V91, P122, DOI 10.3181/00379727-91-22186

[3]

CRUMP KS, 1985, PRINCIPLES HLTH RISK, P279

[4]

FISEROVABERGERO.V, 1983, MODELING INHALATION, V1

[5]

HATTIS D, 1986, CTPID867 MIT CTR TEC

[6]

HOWE RB, 1982, GLOBAL 82 COMPUTER P

[7] AN INVESTIGATION OF UNCERTAINTY AND SENSITIVITY ANALYSIS TECHNIQUES FOR COMPUTER-MODELS [J].

IMAN, RL ;

HELTON, JC .

RISK ANALYSIS, 1988, 8 (01) :71-90

[8]

JOHNSON NL, 1972, DISTRIBUTIONS STATIS

[9] A COMPARISON OF THREE METHODS FOR SELECTING VALUES OF INPUT VARIABLES IN THE ANALYSIS OF OUTPUT FROM A COMPUTER CODE [J].

MCKAY, MD ;

BECKMAN, RJ ;

CONOVER, WJ .

TECHNOMETRICS, 1979, 21 (02) :239-245

[10] BIOLOGICAL ACTIONS AND INTERACTIONS OF TETRACHLOROETHYLENE [J].

REICHERT, D .

MUTATION RESEARCH, 1983, 123 (03) :411-429

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