IGG4 - POSSIBLE MEDIATOR OF ANAPHYLAXIS IN A HEMOPHILIAC PATIENT

被引：28

作者：

SHAKIB, F ^{[1
]}

STANWORTH, DR ^{[1
]}

机构：

[1] UNIV BIRMINGHAM,SCH MED,DEPT IMMUNOL,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND

来源：

CLINICAL ALLERGY | 1979年 / 9卷 / 06期

关键词：

D O I：

10.1111/j.1365-2222.1979.tb00485.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Immunological investigations have been carried out on a haemophiliac patient who had developed severe anaphylaxis to bovine factor VIII administration. Results have shown that the development of anaphylaxis in this patient was associated with a sudden increase in total and specific IgG4 antibodies. The significance of this observation is discussed in relation to current evidence suggesting the involvement of IgG4 antibodies in some anaphylactic conditions. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：597 / 603

页数：7

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