DENTAL EXTRACTIONS IN PATIENTS WITH BLEEDING DISORDERS - THE USE OF FIBRIN GLUE

被引：77

作者：

RAKOCZ, M

MAZAR, A

VARON, D

SPIERER, S

BLINDER, D

MARTINOWITZ, U

机构：

[1] CHAIM SHEBA MED CTR,NATL HEMOPHILIA CTR,IL-52621 TEL HASHOMER,ISRAEL

[2] CHAIM SHEBA MED CTR,DIV PEDIAT & HOSP DENT,IL-52621 TEL HASHOMER,ISRAEL

[3] CHAIM SHEBA MED CTR,DEPT ORAL & MAXILLOFACIAL SURG,IL-52621 TEL HASHOMER,ISRAEL

来源：

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS | 1993年 / 75卷 / 03期

关键词：

D O I：

10.1016/0030-4220(93)90135-Q

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Eighty patients with various bleeding disorders underwent 135 extractions without preventive replacement hematologic therapy. The local hemostatic control involved the use of fibrin glue Beriplast. Secondary bleeding occurred in 9 of 12 patients with severe hemophilia when the concentration of the aprotinin in the fibrin glue was 1,000 KIU/ml. When it was increased to 10,000 KIU/ml and swish and swallow rinses of tranexamic acid before and after the dental extractions were added, only 3 of 25 hemophilia patients suffered from secondary bleeding. Local use of fibrin glue is a safe and cost-effective tool to treat patients with severe bleeding disorders. None of the 43 patients with coagulopathies other than severe hemophilia suffered bleeding after extractions.

引用

页码：280 / 282

页数：3

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