THE EFFECTS OF SHORT-TERM ALCOHOL INTAKE ON CLINIC AND AMBULATORY BLOOD-PRESSURE IN NORMOTENSIVE SOCIAL DRINKERS

被引：32

作者：

OCALLAGHAN, CJ

PHILLIPS, PA

KRUM, H

HOWES, LG

机构：

[1] Clinical Pharmacology and Therapeutics Unit, University of Melbourne, Austin Hospital, Heidelberg

[2] Department of Medicine, University of Melbourne, Austin Hospital, Heidelberg

[3] Department of Clinical Pharmacology, University of New South Wales, St. George Hospital

来源：

AMERICAN JOURNAL OF HYPERTENSION | 1995年 / 8卷 / 06期

关键词：

ALCOHOL; BLOOD PRESSURE; AMBULATORY BLOOD PRESSURE;

D O I：

10.1016/0895-7061(95)00041-M

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Office blood pressure (OBP), ambulatory blood pressure (ABP), and vascular reactivity were measured in 12 normotensive 'social' drinkers (mean alcohol consumption of 9.7 +/- 3.1 g/day) after 4 days of alcohol consumption (1 g/kg/day) and compared with the effects of an isocaloric substitute (sucrose, 1.75 g/kg/day) or no intervention. Alcohol consumption did not affect OBP or 24-mean ABP but appeared to decrease nocturnal systolic and diastolic blood pressure soon after consumption. Although vascular reactivity did not differ between the groups, the blood pressure rise in response to isometric exercise tended to be lower following alcohol. Thus, short-term alcohol ingestion by normotensive 'social' drinkers does not increase office or ambulatory blood pressure.

引用

页码：572 / 577

页数：6

共 24 条

[1]

Klatsky A.L., Friedman G.D., Siegelaub A.B., Gerard M.J., Alcohol consumption and blood pressure, N Eng J Med, 296, pp. 1194-1200, (1977)

[2]

Saunders J.B., Beevers D.G., Paton A., Alcohol-induced hypertension, Lancet, 2, (1981)

[3]

Arkwright P.D., Beilin L.J., Rouse I., Et al., Effects of alcohol use and other aspects of lifestyle on blood pressure levels and prevalence of hypertension in a working population, Circulation, 66, (1982)

[4]

Puddey I.B., Beilin L.J., Vandongen R., Regular alcohol use raises blood pressure in treated hypertensive subjects. A randomised controlled trial, Lancet, 1, pp. 647-651, (1987)

[5]

Puddey I.B., Beilin L.J., Vandongen R., Et al., Evidence for a direct effect of alcohol consumption on blood pressure in normotensive men, Hypertens, 7, pp. 707-713, (1985)

[6]

Potter J.F., Beevers D.G., Pressor effect of alcohol in hypertension, Lancet, 1, pp. 119-122, (1984)

[7]

Malhotra H., Mehta S.R., Mathur D., Khandelwal P.D., Pressor effects of alcohol in normotensive and hypertensive subjects, Lancet, 2, pp. 584-586, (1985)

[8]

Howes L.G., Reid J.L., Decreased vascular responsiveness to noradrenaline following regular ethanol consumption, Br J Clin Pharmacol, 20, pp. 669-674, (1985)

[9]

Howes L.G., Reid J.L., Changes in blood pressure and autonomic reflexes following regular, moderate alcohol consumption, J Hypertens, 4, pp. 421-425, (1986)

[10]

Abe H., Kawaro Y., Ashida T., Et al., Acute and chronic effects of alcohol on 24 hour blood pressure in hypertensive patients, J Hypertens, 8, (1990)

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