The negative evolution found in X-ray clusters of galaxies limits the amount of hot gas available for the inverse Compton scattering of the cosmic microwave background (the Sunyaev-Zel'dovich effect). By the use of a parametrization of the X-ray luminosity function and its evolution in terms of a coalescence model (as presented in the analysis of a flux-limited X-ray cluster sample by Edge et al.), as well as a simple virialized structure for the clusters (which requires a gas-to-total-mass fraction greater than or similar to 0.1 in order to reproduce observed properties of nearby clusters), we show that the Compton distortion gamma parameter is about two orders of magnitude below the current FIRAS upper limits. Concerning the anisotropies imprinted on arcmin scales, they are dominated by the hottest undetected objects. We show that they are negligible (Delta T/T less than or similar to 10(-7)) at wavelengths lambda greater than or similar to 1 mm. At shorter wavelengths, they become more important (Delta T/T similar to 10(-6) at lambda similar to 0.3 mm), but in fact most clusters will produce an isolated and detectable feature in sky maps. After removal of these signals, the fluctuations imprinted by the remaining clusters on the residual radiation are much smaller than 10(-6). The conclusion is that X-ray clusters can be ignored as sources of cosmic microwave background fluctuations.