EFFECTS OF OSMOTIC PRESSURE ON PROCAINE-INDUCED VACUOLATION IN CELL CULTURE

被引：19

作者：

FINNIN, BC

REED, BL

RUFFIN, NE

机构：

[1] Victoria College of Pharmacy, Parkville, Victoria

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1969年 / 21卷 / 02期

关键词：

D O I：

10.1111/j.2042-7158.1969.tb08207.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The effect of increased tonicity on procaine‐induced vacuolation in the H.Ep.2 cell has been investigated. An increase in tonicity equivalent to about 1·3% NaCl was found to reduce the formation of the drug‐induced vacuoles and also to reduce established vacuolation. There appeared to be no difference in the effectiveness of the osmotic adjusting substances used (sodium chloride, sodium sulphate, glucose, fructose and sucrose) when employed in osmotically equivalent amounts. 1969 Royal Pharmaceutical Society of Great Britain

引用

页码：114 / &

共 14 条

[1]

BELKIN M, 1962, J NATL CANCER I, V28, P187

[2]

BUSCHSBAUM R, 1954, ANN NY ACAD SCI, V58, P1303

[3]

FJELDE A, 1955, CANCER, V8, P845, DOI 10.1002/1097-0142(1955)8:4<845::AID-CNCR2820080434>3.0.CO

[4]

2-4

[5]

HONIG J, 1964, ACTA PHARM SUEC, V1, P129

[6] *WEITERE UNTERSUCHUNGEN UBER EINE MITOSEGIFTWIRKUNG VON ALKALOIDEN [J].

LETTRE, H ;

ALBRECHT, M .

HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1951, 287 :58-65

[7] The effect of amines on in vitro bred cells [J].

Lettre, H ;

Albrecht, M .

HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1943, 279 :206-208

[8]

Lettre H, 1941, H-S Z PHYSIOL CHEM, V271, P200, DOI 10.1515/bchm2.1941.271.1-4.200

[9]

MORGAN JF, 1950, P SOC EXP BIOL MED, V73, P1, DOI 10.3181/00379727-73-17557

[10]

POMERAT CM, 1944, P T TEXAS ACAD SCI, V28, P91

← 1 2 →