THE SYNTHESIS OF SUBSTITUTED METHOXY-POLY(ETHYLENEGLYCOL) DERIVATIVES SUITABLE FOR SELECTIVE PROTEIN MODIFICATION

被引：36

作者：

KOGAN, TP ^{[1
]}

机构：

[1] GENENTECH INC, DEPT BIOORGAN CHEM, San Francisco, CA 94080 USA

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 16期

关键词：

D O I：

10.1080/00397919208019100

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The syntheses of methoxypoly(ethyleneglycol) derivatives, functionalized either as hydrazides for the selective attachment of methoxypoly(ethyleneglycol) to carbohydrate domains of glycoproteins, or as iodoacetamides and maleimides for the modification of free sulfhydryl groups, are described.

引用

页码：2417 / 2424

页数：8

共 22 条

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