ASYMMETRIC-SYNTHESIS VIA HETEROCYCLIC INTERMEDIATES .43. ASYMMETRIC-SYNTHESIS OF D-ERYTHRO-SPHINGOSINE

被引：31

作者：

GROTH, U ^{[1
]}

SCHOLLKOPF, U ^{[1
]}

TILLER, T ^{[1
]}

机构：

[1] UNIV GOTTINGEN,INST ORGAN CHEM,TAMMANNSTR 2,W-3400 GOTTINGEN,GERMANY

来源：

TETRAHEDRON | 1991年 / 47卷 / 16-17期

关键词：

D O I：

10.1016/S0040-4020(01)87088-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

D-erythro-Sphingosine 9 is a building block of cerebrosides and glycosphingolipids and was synthesized in 5 steps via an asymmetric aldol addition of the lithiated bislactim ether of cyclo-(L-Val-Gly) 4 to (2E)-hexadecenal (3) in an overall yield of 21 %.

引用

页码：2835 / 2842

页数：8

共 22 条

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