METABOLISM OF CYCLOPENTA(CD)PYRENE AT THE K-REGION BY MICROSOMES AND A RECONSTITUTED CYTOCHROME-P-450 SYSTEM FROM RAT-LIVER

被引：14

作者：

EISENSTADT, E

SHPIZNER, B

GOLD, A

机构：

[1] HARVARD UNIV,SCH PUBL HLTH,TOXICOL LAB,BOSTON,MA 02115

[2] UNIV N CAROLINA,SCH PUBL HLTH,DEPT ENVIRONM HLTH & ENGN,CHAPEL HILL,NC 27514

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1981年 / 100卷 / 03期

关键词：

D O I：

10.1016/0006-291X(81)91917-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：965 / 971

页数：7

共 19 条

[1] HYDROXYLATION OF BENZO[A]PYRENE AND BINDING OF (-)TRANS-7,8-DIHYDROXY-7,8-DIHYDROBENZO[A]PYRENE METABOLITES TO DEOXYRIBONUCLEIC-ACID CATALYZED BY PURIFIED FORMS OF RABBIT LIVER MICROSOMAL CYTOCHROME-P-450 - EFFECT OF 7,8-BENZOFLAVONE, BUTYLATED HYDROXYTOLUENE AND ASCORBIC-ACID [J].

BELVEDERE, G ;

MILLER, H ;

VATSIS, KP ;

COON, MJ ;

GELBOIN, HV .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (12) :1693-1702

[2]

COON MJ, 1977, ACS SYM SER, V44, P46

[3]

DEUTSCH J, 1979, MOL PHARMACOL, V16, P1011

[4] REGIOSELECTIVITY AND STEREOSELECTIVITY OF VARIOUS FORMS OF PURIFIED CYTOCHROME-P-450 IN METABOLISM OF BENZO[A]PYRENE AND (-) TRANS-7,8-DIHYDROXY-7,8-DIHYDROBENZO[A]PYRENE AS SHOWN BY PRODUCT FORMATION AND BINDING TO DNA [J].

DEUTSCH, J ;

LEUTZ, JC ;

YANG, SK ;

GELBOIN, HV ;

CHIANG, YL ;

VATSIS, KP ;

COON, MJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (07) :3123-3127

[5] CYCLOPENTA[C,D]PYRENE - HIGHLY MUTAGENIC POLYCYCLIC AROMATIC HYDROCARBON [J].

EISENSTADT, E ;

GOLD, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (04) :1667-1669

[6]

ESTABROOK RW, 1978, POLYCYCLIC HYDROCARB, P285

[7]

GOLD A, 1980, CANCER RES, V40, P3940

[8]

GOLD A, 1978, TETRAHEDRON LETT, V46, P4491

[9]

GOLD A, CANCER RES

[10]

GOLD A, 1979, J CHEM SOC CHEM COMM, V20, P903

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