PARENTAL CHILDHOOD RESPIRATORY ILLNESS AND RESPIRATORY ILLNESS IN THEIR INFANTS

被引:20
作者
CAMILLI, AE
HOLBERG, CJ
WRIGHT, AL
TAUSSIG, LM
机构
[1] ARIZONA HLTH SCI CTR,DEPT PEDIAT,TUCSON,AZ 85724
[2] ARIZONA HLTH SCI CTR,SIEELE MEM CHILDRENS RES CTR,TUCSON,AZ 85724
关键词
PARENTAL ASTHMA; BRONCHIOLITIS; BRONCHITIS; CROUP; WHEEZING; NON-WHEEZING LOWER RESPIRATORY ILLNESS;
D O I
10.1002/ppul.1950160502
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Parental histories of childhood respiratory trouble (CRT) were examined as risk factors for lower respiratory tract illnesses in healthy infants enrolled in the Children's Respiratory Study, Tucson, Arizona. A parental history of childhood respiratory trouble before age 16 was a risk factor for infantile lower respiratory tract illnesses (LRIs). Early age of onset of the parental CRT and those illnesses described as asthma or bronchiolitis showed the greatest risk: odds ratio = 2.8, P < 0.05. After controlling for known and suspected confounders, a parental history of CRT described as asthma or bronchiolitis with onset before age 3 was associated with wheezing LRIs in their children, with an odds ratio of 2.6, P < 0.05. A parental history of CRT described as bronchitis/croup was associated with nonwheezing LRIs in their children: odds ratio = 2.2, P < 0.05. These findings suggest a familial component to childhood respiratory trouble which may have a hereditary basis. (C) 1993 Wiley-Liss, Inc.
引用
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页码:275 / 280
页数:6
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