SYNTHESIS OF MONOMORIN-I, A TRAIL PHEROMONE OF THE PHARAO ANT (MONOMORIUM-PHARAONIS)

被引：18

作者：

VAVRECKA, M ^{[1
]}

HESSE, M ^{[1
]}

机构：

[1] UNIV ZURICH,INST ORGAN CHEM,WINTERTHURERSTR 190,CH-8057 ZURICH,SWITZERLAND

来源：

HELVETICA CHIMICA ACTA | 1991年 / 74卷 / 02期

关键词：

D O I：

10.1002/hlca.19910740221

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Katalytic hydrogenation of the 4-nitroalkanone 5 yielded the cis-pyrrolidine ester 6 (Scheme). The preparation of 5 was accomplished by ethanolysis of the nitrocyclohexanone derivative 4. Iodination at C(alpha) of 6, followed by cyclization, gave a nearly 5:6 mixture of the two C(5)-epimers 10/9 of octahydroindolizine. Epimerisation of the underised 10 to 9 and subsequent transformation of the latter gave racemic monomorine I (1; 34% yield from 5).

引用

页码：438 / 444

页数：7

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