SYNTHESIS OF 3-ARYLPYRROLES AND 3-PYRROLYLACETYLENES BY PALLADIUM-CATALYZED COUPLING REACTIONS

被引：100

作者：

ALVAREZ, A

GUZMAN, A

RUIZ, A

VELARDE, E

MUCHOWSKI, JM

机构：

[1] SYNTEX INC,INST ORGAN CHEM,3401 HILLVIEW AVE,PALO ALTO,CA 94304

[2] SYNTEX SA,DIV INVEST,MEXICO CITY 10,DF,MEXICO

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 06期

关键词：

D O I：

10.1021/jo00032a011

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficacious methods for the synthesis of 3-arylpyrroles or 3-pyrrolylacetylenes are described based on the palladium-catalyzed coupling of appropriate 1-(triisopropylsilyl)-3-substituted pyrroles with aryl halides or monosubstituted acetylenes and subsequent tetrabutylammonium fluoride desilylation.

引用

页码：1653 / 1656

页数：4

共 33 条

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