THE CHEMISTRY OF CYCLOPROPYLMETHYL AND RELATED RADICALS

被引：148

作者：

NONHEBEL, DC

机构：

[1] Dept. of Pure and Applied Chemistry, University of Strathclyde, Glasgow G1 1XL, United Kingdom

[2] King's College, University of London

[3] University of Oxford

[4] Royal Society of Edinburgh

来源：

CHEMICAL SOCIETY REVIEWS | 1993年 / 22卷 / 05期

关键词：

D O I：

10.1039/cs9932200347

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The use of ring opening rearrangement of cyclopropylmethyl radicals to but-3-enyl radicals as radical clocks and as probes of reaction mechanism is discussed relation to a variety of both enzyme-catalysed and chemical reactions. Similar studies using heterocyclic analogues, e.g. oxiranylmethyl radicals, are also reported. Factors which influence both the rate and regioselectivity of ring opening of cyclopropylmethyl and related radicals have been analysed. The use of this rearrangement in synthetic methodology has also been surveyed.

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页码：347 / 359

页数：13

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