CONTRALATERAL SUPPRESSION OF TRANSIENT EVOKED OTOACOUSTIC EMISSIONS IN GUINEA-PIGS - EFFECTS OF GENTAMICIN

被引：16

作者：

ARAN, JM ^{[1
]}

ERRE, JP ^{[1
]}

AVAN, P ^{[1
]}

机构：

[1] UNIV AUVERGNE,FAC MED,BIOPHYS LAB,CLERMONT FERRAND,FRANCE

来源：

BRITISH JOURNAL OF AUDIOLOGY | 1994年 / 28卷 / 4-5期

关键词：

TRANSIENT OTOACOUSTIC EMISSIONS; SUPPRESSION; EFFERENT; GENTAMICIN;

D O I：

10.3109/03005369409086576

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

A single injection of gentamicin in the awake guinea-pig induces a transient blockade of the suppression by contralateral white noise of tone-pip evoked compound action potential (Smith et al., 1994). We report here the reversible blockade, in exactly the same experimental conditions, of the suppression of click-evoked otoacoustic emissions. These observations confirm the transient action of gentamicin al the medial efferent/outer hair cell synapse, likely via the reversible blockade of calcium channels observed in vitro (Dulon er al., 1989).

引用

页码：267 / 271

页数：5

共 14 条

[1]

ARAN JM, 1990, ADV AUDIOL, V7, P42

[2] EVOKED OTOACOUSTIC EMISSIONS IN GUINEA-PIG - BASIC CHARACTERISTICS [J].

AVAN, P ;

LOTH, D ;

MENGUY, C ;

TEYSSOU, M .

HEARING RESEARCH, 1990, 44 (2-3) :151-160

[3] CONTRALATERAL SUPPRESSION OF NONLINEAR CLICK-EVOKED OTOACOUSTIC EMISSIONS [J].

BERLIN, CI ;

HOOD, LJ ;

WEN, H ;

SZABO, P ;

CECOLA, RP ;

RIGBY, P ;

JACKSON, DF .

HEARING RESEARCH, 1993, 71 (1-2) :1-11

[4] ACOUSTIC DISTORTION PRODUCTS CAN BE USED TO MONITOR THE EFFECTS OF CHRONIC GENTAMICIN TREATMENT [J].

BROWN, AM ;

MCDOWELL, B ;

FORGE, A .

HEARING RESEARCH, 1989, 42 (2-3) :143-156

[5] AUDITORY-NERVE FIBER ACTIVITY INFLUENCED BY CONTRALATERAL EAR SOUND STIMULATION [J].

BUNO, W .

EXPERIMENTAL NEUROLOGY, 1978, 59 (01) :62-74

[6] AMINOGLYCOSIDE ANTIBIOTICS IMPAIR CALCIUM ENTRY BUT NOT VIABILITY AND MOTILITY IN ISOLATED COCHLEAR OUTER HAIR-CELLS [J].

DULON, D ;

ZAJIC, G ;

ARAN, JM ;

SCHACHT, J .

JOURNAL OF NEUROSCIENCE RESEARCH, 1989, 24 (02) :338-346

[7]

DULON D, 1993, CR HEBD ACAD SCI, V316, P676

[8]

HIEL H, 1993, AUDIOLOGY, V32, P78

[9]

HUY PTB, 1981, J INFECT DIS, V143, P476

[10] BLOCKAGE OF THE TRANSDUCTION CHANNELS OF HAIR-CELLS IN THE BULLFROGS SACCULUS BY AMINOGLYCOSIDE ANTIBIOTICS [J].

KROESE, ABA ;

DAS, A ;

HUDSPETH, AJ .

HEARING RESEARCH, 1989, 37 (03) :203-217

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