METABOLIC OXIDATION OF THE PYRROLE RING - STRUCTURE AND ORIGIN OF SOME URINARY METABOLITES OF THE ANTIHYPERTENSIVE PYRROLYLPYRIDAZINAMINE, MOPIDRALAZINE .3. STUDIES WITH THE C-13-LABELED DRUG

被引：7

作者：

ASSANDRI, A

TARZIA, G

BELLASIO, E

CIABATTI, R

TUAN, G

FERRARI, P

ZERILLI, L

LANFRANCHI, M

PELIZZI, G

机构：

[1] GRP LEPETIT SPA,RES LABS,I-20158 MILAN,ITALY

[2] UNIV PARMA,CNR,INST CHEM,DEPT DIFFRACTOMETRY,I-43100 PARMA,ITALY

来源：

关键词：

D O I：

10.3109/00498258709043963

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：559 / 573

页数：15

共 30 条

[1] ASSANDRI A, 1985, XENOBIOTICA, V15, P1089, DOI 10.3109/00498258509049103
[2] METABOLIC PATHWAYS OF THE ANTI-HYPERTENSIVE AGENT, N-(2,5-DIMETHYL-1H-PYRROL-1-YL)-6-(4-MORPHOLINYL)-3-PYRIDAZINAMINE HYDROCHLORIDE .1. STUDIES IN THE RAT
ASSANDRI, A
PERAZZI, A
BALDOLI, E
FERRARI, P
RIPAMONTI, A
BELLASIO, E
TUAN, G
ZERILLI, LF
TARZIA, G
[J]. XENOBIOTICA, 1985, 15 (12) : 1069 - 1087
[3] ASSANDRI A, 1985, ARZNEIMITTEL-FORSCH, V35, P508
[4] ASSANDRI A, 1985, DRUG METABOLISM DISP, V12, P257
[5] BALDOLI E, 1985, ARZNEIMITTELFORSCH, V35-1, P818
[6] MOLYBDENUM HYDROXYLASES AS DRUG-METABOLIZING-ENZYMES
BEEDHAM, C
[J]. DRUG METABOLISM REVIEWS, 1985, 16 (1-2) : 119 - 156
[7] BELLASIO E, 1972, FARMACO-ED SCI, V27, P591
[8] ANTIHYPERTENSIVES - N-1H-PYRROL-1-YL-3-PYRIDAZINAMINES
BELLASIO, E
CAMPI, A
DIMOLA, N
BALDOLI, E
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (08) : 1077 - 1083
[9] BELLASIO E, 1969, Patent No. 1157642
[10] DIMOLA N, 1985, J LABELLED COMPD RAD, V22, P1299