WATER-DRAGGING EFFECT - A NEW EXPERIMENTAL HYDRATION PARAMETER RELATED TO HYDROGEN-BOND-DONOR ACIDITY

被引：17

作者：

FAN, WZ ^{[1
]}

ELTAVAR, N ^{[1
]}

TESTA, B ^{[1
]}

KIER, LB ^{[1
]}

机构：

[1] UNIV LAUSANNE,ECOLE PHARM,INST CHIM THERAPEUT,PL CHATEAU,CH-1005 LAUSANNE,SWITZERLAND

来源：

JOURNAL OF PHYSICAL CHEMISTRY | 1990年 / 94卷 / 12期

关键词：

D O I：

10.1021/j100375a003

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The solubility of water in di-n-butyl ether (0.15 wt %) is increased by solutes partitioning between an aqueous phase and the solvent. The "water-dragging effect" of 32 solutes was measured and found to be exquisitely sensitive to structural factors. Evidence is given indicating that solute-water interactions in di-n-butyl ether are governed overwhelmingly (95% of the variance) by the H-bond-donor capacity of the solutes. The method appears as a promising means of measuring the H-bond-donor acidity of solutes. © 1990 American Chemical Society.

引用

页码：4764 / 4766

页数：3

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