HIGH-DENSITY LIPOPROTEIN AS CARRIER FOR AMYLOID-RELATED PROTEIN SAA IN RABBIT SERUM

被引：74

作者：

SKOGEN, B

BORRESEN, AL

NATVIG, JB

BERG, K

MICHAELSEN, TE

机构：

[1] UNIV OSLO,INST MED GENET,OSLO,NORWAY

[2] NATL INST PUBL HLTH,DEPT IMMUNOL,OSLO,NORWAY

来源：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 1979年 / 10卷 / 01期

关键词：

D O I：

10.1111/j.1365-3083.1979.tb01332.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this study we present evidence that SAA is complexed to high density lipoprotein (HDL) in rabbit serum and is co‐isolated with HDL apoproteins. The binding of SAA to HDL seems to be quite strong, judged from affinity chromatography experiments. The studies did not reveal any interaction between SAA and albumin, and there was no evidence that SAA could complex to itself. By isolation of HDL apoproteins, SAA seems to behave like other known apoproteins and may he characterized as an apoprotein that is present in normal serum in very low concentration but increases in concentration under different unphysiological circumstances. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：39 / 45

页数：7

共 29 条

[1] ISOLATION AND CHARACTERIZATION OF AMYLOID-RELATED SERUM-PROTEIN SAA AS A LOW-MOLECULAR WEIGHT PROTEIN [J].