A NEW METHOD FOR SEPARATION AND QUANTITATIVE DETERMINATION OF METABOLITES OF TRYPTAMINES IN BIOLOGICAL MATERIAL

被引：7

作者：

ISKRIC, S

STANCIC, L

KVEDER, S

机构：

[1] Tracer Laboratory, Department of Organic Chemistry and Biochemistry, Institute Ruder Boškovic

来源：

CLINICA CHIMICA ACTA | 1969年 / 25卷 / 03期

关键词：

D O I：

10.1016/0009-8981(69)90205-8

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

A procedure for assay of 5-hydroxytryptamine and its metabolites-5-hy-droxyindole-3-acetic acid, 5-hydroxyindole-3-carboxylic acid, 5-hydroxytryptophol and 5-hydroxyindole-3-aldehyde-after separation by column chromatography, followed by spectrofluorometric determination, was elaborated. The same method has proved to be applicable also to tryptamine and its metabolites, as well as to 5-methoxytryptamine and its metabolites. © 1969.

引用

页码：435 / &

共 12 条

[1] AN IMPROVED METHOD FOR FLUORIMETRIC DETERMINATION OF 5-HYDROXYTRYPTAMINE IN TISSUES [J].

ANDEN, NE ;

MAGNUSSON, T .

ACTA PHYSIOLOGICA SCANDINAVICA, 1967, 69 (1-2) :87-+

[2] USE OF SEPHADEX G-10 IN REMOVAL OF INORGANIC SALTS AND UREA FROM RAT AND HUMAN URINE PRIOR TO CHROMATOGRAPHY OF 5-HYDROXYINDOLE METABOLITES [J].

CONTRACT.SF ;

JOMAIN, P .

CLINICA CHIMICA ACTA, 1966, 14 (04) :535-&

[3] FORMATION OF 5-HYDROXYTRYPTOPHOL IN BRAIN IN VITRO [J].

ECCLESTON, D ;

MOIR, ATB ;

READING, HW ;

RITCHIE, IM .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1966, 28 (03) :367-+

[4]

GARATTINI S, 1968, ADVANCES PHARMACO B5, V6, P123

[5]

ISKRIC S, 1969, 6 M FED EUR BIOCH SO, P179

[6]

Keglevic D, 1968, Adv Pharmacol, V6, P79

[7]

Maickel R P, 1968, Adv Pharmacol, V6, P71

[8]

MITCHELL J, 1953, ORG ANALYSIS, V1, P282

[9]

OATES JOHN A., 1961, METHODS MED RES, V9, P169

[10] A SENSITIVE AND SPECIFIC FLUORESCENCE ASSAY FOR TISSUE SEROTONIN [J].

SNYDER, SH ;

AXELROD, J ;

ZWEIG, M .

BIOCHEMICAL PHARMACOLOGY, 1965, 14 (05) :831-&

← 1 2 →