THE AEDES-AEGYPTI GENOME - COMPLEXITY AND ORGANIZATION

被引：47

作者：

WARREN, AM ^{[1
]}

CRAMPTON, JM ^{[1
]}

机构：

[1] UNIV LIVERPOOL,LIVERPOOL SCH TROP MED,WOLFSON UNIT MOLEC GENET,PEMBROKE PL,LIVERPOOL L3 5QA,ENGLAND

来源：

GENETICAL RESEARCH | 1991年 / 58卷 / 03期

基金：

英国惠康基金;

关键词：

D O I：

10.1017/S0016672300029979

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We describe the use of DNA reassociation kinetics to determine the total genome size and complexity together with the individual complexity and copy number of the single copy, middle repetitive and highly repeated DNA fractions of cell line and larval DNA from the mosquito, Aedes aegypti. The genome of Ae. aegypti is both large and complex, being one third the size of the human genome, and exhibits a short period interspersed repeat pattern. The implications of patterns of sequence arrangement and genome complexities for experiments aimed at isolating specific classes of DNA sequences, such as mobile genetic elements, are discussed.

引用

页码：225 / 232

页数：8

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