BACILLUS CALMETTE-GUERIN AND INTERLEUKIN-2 FOR TREATMENT OF SUPERFICIAL BLADDER-CANCER

被引：13

作者：

COCKETT, ATK ^{[1
]}

DAVIS, RS ^{[1
]}

COS, LR ^{[1
]}

WHEELESS, LL ^{[1
]}

机构：

[1] UNIV ROCHESTER,SCH MED & DENT,DEPT PATHOL & LAB MED,ROCHESTER,NY 14642

来源：

JOURNAL OF UROLOGY | 1991年 / 146卷 / 03期

关键词：

CARCINOMA; BCG VACCINE; BLADDER NEOPLASMS; INTERLEUKIN-2;

D O I：

10.1016/S0022-5347(17)37916-8

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A total of 22 patients with bladder cancer received bacillus Calmette-Guerin (BCG) and interleukin-2. Significant bladder tumor remissions were noted in 15 of 17 patients (88%). Of 5 patients with carcinoma in situ 1 was noncompliant and he died of carcinoma in situ. The other 4 patients are in remission. BCG alone was instilled in 22 additional patients with superficial bladder cancer. The remission rates were encouraging. Of the 22 patients 13 (59%) had remission of the bladder tumor. A half dose of BCG (60 mg.) is adequate when given weekly for 6 weeks. Maintenance therapy is important as noted in both of our clinical arms. BCG and interleukin-2 therapy results in a higher remission rate.

引用

页码：766 / 770

页数：5

共 13 条

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