SELECTIVE IMPAIRMENTS IN MANAGERIAL KNOWLEDGE FOLLOWING PREFRONTAL CORTEX DAMAGE

被引：115

作者：

SIRIGU, A ^{[1
]}

ZALLA, T ^{[1
]}

PILLON, B ^{[1
]}

GRAFMAN, J ^{[1
]}

AGID, Y ^{[1
]}

DUBOIS, B ^{[1
]}

机构：

[1] NINCDS, COGNIT NEUROSCI SECT, BETHESDA, MD 20892 USA

来源：

CORTEX | 1995年 / 31卷 / 02期

关键词：

D O I：

10.1016/S0010-9452(13)80364-4

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Script generation was investigated in patients with lesions in the prefrontal (n=9) and posterior (n=8) cortical regions and in normal subjects (n=16). Three different activities ranging in degree of familiarity were studied. Frontal patients did not differ from patients with posterior lesion and Normal subjects in the number of actions evoked, mean evocation time, or centrality. Impairments in script information processing were observed only in patients with prefrontal lesions, and for the three types of scripts. Specifically these patients made errors in ordering actions in the correct temporal sequence, failed to close scripts and to remain within the stated boundaries, and made deviant estimates of action importance. The results suggest that pre-frontal cortical lesions provoke a selective impairment in managerial knowledge (Grafman, 1989) that may contribute to difficulties in the formulation and execution of plans.

引用

页码：301 / 316

页数：16

共 27 条

[1] THE REPRESENTATION OF SCRIPTS IN MEMORY [J].