MALIGNANT HISTIOCYTOSIS OF THE INTESTINE

被引:25
作者
HODGES, JR
ISAACSON, P
SMITH, CL
SWORN, MJ
机构
[1] UNIV SOUTHAMPTON HOSP,MED UNIT,SOUTHAMPTON,HAMPSHIRE,ENGLAND
[2] UNIV SOUTHAMPTON HOSP,DEPT PATHOL,SOUTHAMPTON,HAMPSHIRE,ENGLAND
关键词
D O I
10.1007/BF01333708
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Four cases of malignant histiocytosis of the intestine (MHI) are described in detail, with emphasis on the clinical features and laboratory findings that may lead to a diagnosis. MHI is a rapidly progressive, usually fatal condition, which may occur in a setting of adult celiac disease or apparently spontaneously; all patients, however, have villous atrophy and crypt hyperplasia of the jejunum. Characteristic symptoms are malaise, weight loss, abdominal pain, and diarrhea followed, after a period of weeks or months, by acute small intestinal obstruction, perforation, or bleeding. Because of the high mortality associated with MHI, suggestive symptomatology and investigations should, in the absence of a definitive diagnosis, lead to an urgent laparotomy with a view to chemotherapy if the diagnosis is made. © 1979 Digestive Disease Systems, Inc.
引用
收藏
页码:631 / 638
页数:8
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