PHOSPHOROTHIOATE AND NORMAL OLIGODEOXYRIBONUCLEOTIDES WITH 5'-LINKED ACRIDINE - CHARACTERIZATION AND PRELIMINARY KINETICS OF CELLULAR UPTAKE

被引：119

作者：

STEIN, CA ^{[1
]}

MORI, K ^{[1
]}

LOKE, SL ^{[1
]}

SUBASINGHE, C ^{[1
]}

SHINOZUKA, K ^{[1
]}

COHEN, JS ^{[1
]}

NECKERS, LM ^{[1
]}

机构：

[1] NCI,BLDG 10-6N105,BETHESDA,MD 20892

来源：

GENE | 1988年 / 72卷 / 1-2期

关键词：

D O I：

10.1016/0378-1119(88)90160-6

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：333 / 341

页数：9

共 15 条

[1] NUCLEIC-ACID BINDING-MOLECULES WITH HIGH-AFFINITY AND BASE SEQUENCE SPECIFICITY - INTERCALATING AGENTS COVALENTLY LINKED TO OLIGODEOXYNUCLEOTIDES [J].

ASSELINE, U ;

DELARUE, M ;

LANCELOT, G ;

TOULME, F ;

THUONG, NT ;

MONTENAYGARESTIER, T ;

HELENE, C .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (11) :3297-3301

[2] OLIGODEOXYNUCLEOTIDES COVALENTLY LINKED TO INTERCALATING DYES AS BASE SEQUENCE-SPECIFIC LIGANDS - INFLUENCE OF DYE ATTACHMENT SITE [J].

ASSELINE, U ;

TOULME, F ;

THUONG, NT ;

DELARUE, M ;

MONTENAYGARESTIER, T ;

HELENE, C .

EMBO JOURNAL, 1984, 3 (04) :795-800

[3] NUCLEOSIDE PHOSPHOROTHIOATES [J].

ECKSTEIN, F .

ANNUAL REVIEW OF BIOCHEMISTRY, 1985, 54 :367-402

[4] A C-MYC ANTISENSE OLIGODEOXYNUCLEOTIDE INHIBITS ENTRY INTO S-PHASE BUT NOT PROGRESS FROM G0 TO G1 [J].

HEIKKILA, R ;

SCHWAB, G ;

WICKSTROM, E ;

LOKE, SL ;

PLUZNIK, DH ;

WATT, R ;

NECKERS, LM .

NATURE, 1987, 328 (6129) :445-449

[5] OLIGODEOXYNUCLEOTIDES COVALENTLY LINKED TO INTERCALATING AGENTS - A NEW CLASS OF GENE REGULATORY SUBSTANCES [J].

HELENE, C ;

MONTENAYGARESTIER, T ;

SAISON, T ;

TAKASUGI, M ;

TOULME, JJ ;

ASSELINE, U ;

LANCELOT, G ;

MAURIZOT, JC ;

TOULME, F ;

THUONG, NT .

BIOCHIMIE, 1985, 67 (7-8) :777-783

[6]

HELENE C, 1986, DNA LIGAND INTERACTI

[7] EVIDENCE FOR A COMPETING CONDENSATION REACTION IN THE ALLOXAN SYNTHESIS OF FLAVINS - SYNTHESIS AND CRYSTAL AND MOLECULAR-STRUCTURES OF 7-CHLORO-8-METHYLALLOXAZINE AND 7,10-DIMETHYL-8-[(2-HYDROXYETHYL)THIO]ISOALLOXAZINE [J].

KUMAR, V ;

WOODE, KA ;

BRYAN, RF ;

AVERILL, BA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (03) :490-496

[8] PROTON AND PHOSPHORUS NUCLEAR MAGNETIC-RESONANCE STUDIES OF AN OLIGOTHYMIDYLATE COVALENTLY LINKED TO AN ACRIDINE DERIVATIVE AND OF ITS BINDING TO COMPLEMENTARY SEQUENCES [J].

LANCELOT, G ;

ASSELINE, U ;

THUONG, NT ;

HELENE, C .

BIOCHEMISTRY, 1985, 24 (10) :2521-2529

[9] PHOSPHOROTHIOATE-MODIFIED OLIGODEOXYRIBONUCLEOTIDES .3. NMR AND UV SPECTROSCOPIC STUDIES OF THE RP-RP, SP-SP, AND RP-SP DUPLEXES, [D(GGSAATTCC)]2, DERIVED FROM DIASTEREOMERIC O-ETHYL PHOSPHOROTHIOATES [J].

LAPLANCHE, LA ;

JAMES, TL ;

POWELL, C ;

WILSON, WD ;

UZNANSKI, B ;

STEC, WJ ;

SUMMERS, MF ;

ZON, G .

NUCLEIC ACIDS RESEARCH, 1986, 14 (22) :9081-9093

[10] PHOSPHOROTHIOATE ANALOGS OF OLIGODEOXYNUCLEOTIDES - INHIBITORS OF REPLICATION AND CYTOPATHIC EFFECTS OF HUMAN-IMMUNODEFICIENCY-VIRUS [J].

MATSUKURA, M ;

SHINOZUKA, K ;

ZON, G ;

MITSUYA, H ;

REITZ, M ;

COHEN, JS ;

BRODER, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (21) :7706-7710

← 1 2 →