URIC-ACID EXCRETION - QUANTITATIVE ASSESSMENT FROM SPOT, MIDMORNING SERUM AND URINE SAMPLES

被引：50

作者：

SIMKIN, PA

HOOVER, PL

PAXSON, CS

WILSON, WF

机构：

[1] AMER LAKE VET ADM HOSP, AMER LAKE, WA USA

[2] MADIGAN ARMY HOSP, FT LEWIS, TACOMA, WA USA

来源：

ANNALS OF INTERNAL MEDICINE | 1979年 / 91卷 / 01期

关键词：

D O I：

10.7326/0003-4819-91-1-44

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Uric acid excretion can be measured in milligrams of urinary uric acid per decilitre of glomerular filtrate by obtaining the product of urinary uric acid and serum creatinine concentrations and dividing by the urine creatinine (all concentrations in mg/dL). In 29 normal adult men, the excretion rate in spot, midmorning samples was 0.4 ± 0.1 (SD) mg of uric acid per decilitre of glomerular filtrate. Eight of 36 untreated gouty men excreted uric acid at a rate more than three standard deviations above normal. Excretion of uric acid is conveniently and physiologically assessed by this simple method.

引用

页码：44 / 47

页数：4

共 17 条

[1] RECENT ADVANCES IN IDENTIFICATION OF ENZYME ABNORMALITIES UNDERLYING EXCESSIVE PURINE SYNTHESIS IN MAN [J].