ADRENAL SCINTIGRAPHY WITH 19-IODOCHOLESTEROL-I-131 IN THE DIAGNOSIS OF CUSHINGS-SYNDROME ASSOCIATED WITH ADRENAL-TUMOR

被引:5
作者
BARLIEV, GB
机构
[1] Institute of Endocrinology and Gerontology, Radioisotope Laboratory, Medical Academy, Sofia
来源
EUROPEAN JOURNAL OF NUCLEAR MEDICINE | 1979年 / 4卷 / 06期
关键词
D O I
10.1007/BF00300844
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Seven patients with Cushing's syndrome secondary to adrenocortical tumors were studied using 131I-19-iodocholesterol. The diagnosis of all cases were verified histologically. In three cases with adenoma the uptake of the tracer was in the tumor only, while the two patients with adrenocortical carcinoma failed to show adrenal accumulation of the labelled compound. In two patients there was a hyperplasia-like scintigraphic pattern, while the stimulation and suppression biochemical tests suggested adrenal tumor. One of these cases was verified as a mixed form (adenoma plus hyperplasia), and the tumor bearing gland was significantly larger on the scan which helped the preoperative localization. In the other case, verified as bilateral multiple adrenocortical adenomas, the autonomus function of both adrenals was proved by dexamethasone suppression scanning. It seens reasonable to use the latter as an adjunctive diagnostic procedure in patients where there is a discrepancy between the standart scintiscan and the biochemical indexes of adrenal hyperfunction. © 1979 Springer-Verlag.
引用
收藏
页码:449 / 451
页数:3
相关论文
共 8 条