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VENTILATION AND CHEMOREFLEXES DURING ENFLURANE SEDATION AND ANESTHESIA IN MAN

被引：78
作者：
KNILL, RL
MANNINEN, PH
CLEMENT, JL
机构：
[1] Department of Anaesthesia, University Hospital, University of Western Ontario, London, N6A 5A5, Ontario
来源：
CANADIAN ANAESTHETISTS SOCIETY JOURNAL | 1979年 / 26卷 / 05期
关键词：
D O I：
10.1007/BF03006447
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
Enflurane sedation and anaesthesia in healthy fit subjects reduced ventilation and the response to carbon dioxide, hypoxaemia and a low dose of doxapram, all in a dose-related fashion. Comparing the three chemoreflexes tested, the response to hypoxaemia and doxapram were the more profoundly impaired; they were nearly totally abolished by anaesthesia. These effects of enflurane on chemoreflex activities are qualitatively similar to those previously observed with halothane. © 1979 Canadian Anesthesiologists.
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页码：353 / 360
页数：8
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