METABOLISM AND ANTICONVULSANT ACTIVITY OF DEUTERATED N-DEMETHYLDIAZEPAM

被引：15

作者：

MARCUCCI, F ^{[1
]}

MUSSINI, E ^{[1
]}

MARTELLI, P ^{[1
]}

GUAITANI, A ^{[1
]}

GARATTINI, S ^{[1
]}

机构：

[1] IST RICERCHE FARMACOL MARIO NEGRI, ERITREA 62, 20157 MILAN, ITALY

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1973年 / 62卷 / 11期

关键词：

D O I：

10.1002/jps.2600621144

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1900 / 1902

页数：3

共 9 条

[1] BENZODIAZEPINE METABOLISM IN-VITRO [J].

GARATTINI, S ;

MARCUCCI, F ;

MUSSINI, E .

DRUG METABOLISM REVIEWS, 1972, 1 (02) :291-309

[2]

LITCHFIELD JT, 1949, J PHARMACOL EXP THER, V96, P99

[3]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[4] A METHOD FOR GAS CHROMATOGRAPHIC DETERMINATION OF BENZODIAZEPINES [J].

MARCUCCI, F ;

FANELLI, R ;

MUSSINI, E .

JOURNAL OF CHROMATOGRAPHY, 1968, 37 (02) :318-&

[5] SPECIES DIFFERENCE IN DIAZEPAM METABOLISM AND ANTICONVULSANT EFFECT [J].

MARCUCCI, F ;

GUAITANI, A ;

KVETINA, J ;

MUSSINI, E ;

GARATTINI, S .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1968, 4 (04) :467-+

[6] ANTICONVULSANT ACTIVITY AND BRAIN LEVELS OF DIAZEPAM AND ITS METABOLITES IN MICE [J].

MARCUCCI, F ;

MUSSINI, E ;

GUAITANI, A ;

FANELLI, R ;

GARATTINI, S .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1971, 16 (03) :311-+

[7] METABOLISM OF DIAZEPAM BY LIVER MICROSOMAL ENZYMES OF RATS AND MICE [J].

MARCUCCI, F ;

FANELLI, R ;

MUSSINI, E ;

GARATTINI, S .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1969, 7 (03) :307-+

[8] SPECIES DIFFERENCES IN DIAZEPAM METABOLISM .1. METABOLISM OF DIAZEPAM METABOLITES [J].

MARCUCCI, F ;

MUSSINI, E ;

FANELLI, R ;

GARATTINI, S .

BIOCHEMICAL PHARMACOLOGY, 1970, 19 (05) :1847-+

[9]

RANDALL LO, 1965, CURR THER RES CLIN E, V7, P590

← 1 →