PRODUCTION OF 2-KETOBUTYRIC ACID FROM 1,2-BUTANEDIOL BY RESTING CELLS OF RHODOCOCCUS-EQUI IFO-3730

被引：8

作者：

NAKAHARA, T ^{[1
]}

NAKAJIMAKAMBE, T ^{[1
]}

SATO, S ^{[1
]}

机构：

[1] UNIV TSUKUBA,INST APPL BIOCHEM,TSUKUBA,IBARAKI 305,JAPAN

来源：

BIOTECHNOLOGY LETTERS | 1994年 / 16卷 / 03期

关键词：

D O I：

10.1007/BF00134623

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Various microorganisms were screened for their ability to produce 2-ketobutyric acid (2-KBA) from 1,2-butanediol (1,2-BD). Among them, Rhodococcus equi IFO 3730 was selected as the best strain. The various culture and reaction conditions were optimized using this strain. Limitation of thiamine in the growing medium was found to be effective. The resting cells of the strain grown on 1,2-propanediol as the carbon source yielded 15.7 g/l of 2-KBA from 20 g/l of 1,2-BD after 32 h incubation at 30 degrees C in the reaction mixture under optimal conditions.

引用

页码：263 / 268

页数：6

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