BONE INDUCTION BY COMPOSITES OF BIORESORBABLE CARRIERS AND DEMINERALIZED BONE IN RATS - A COMPARATIVE-STUDY OF FIBRIN-COLLAGEN PASTE, FIBRIN SEALANT, AND POLYORTHOESTER WITH GENTAMICIN

被引：27

作者：

PINHOLT, EM

SOLHEIM, E

BANG, G

SUDMANN, E

机构：

[1] UNIV OSLO, RIKSHOSP, INST SURG RES, OSLO, NORWAY

[2] UNIV BERGEN, DEPT ORAL PATHOL & FORENS ODONTOL, N-5014 BERGEN, NORWAY

[3] UNIV BERGEN, HAGAVIK ORTHOPAED HOSP, N-5014 BERGEN, NORWAY

来源：

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 1992年 / 50卷 / 12期

关键词：

D O I：

10.1016/0278-2391(92)90231-N

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Host tissue response and heterotopic osteoinduction by composites of demine4alized bone matrix and three different substances used as bioresorbable carriers implanted in the abdominal muscles were evaluated by strontium 85 uptake and histology 4 weeks postoperatively in 60 male Wistar rats. Both fibrin-collagen paste and fibrin sealent inhibited bone induction and produced a chronic inflamation; part of the fibrin-collagen paste was still present at 4 weeks. Polyorthoester with gentamicin was almost completely absorbed, induced minimal tissue reaction, and did not inhibit osteoinduction. © 1992.

引用

页码：1300 / 1304

页数：5

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