VODKA CONSUMPTION, TOBACCO SMOKING AND RISK OF GASTRIC-CANCER IN POLAND

被引:55
作者
JEDRYCHOWSKI, W
BOEING, H
WAHRENDORF, J
POPIELA, T
TOBIASZADAMCZYK, B
KULIG, J
机构
[1] GERMAN CANC RES CTR, INST EPIDEMIOL & BIOMETRY, W-6900 HEIDELBERG 1, GERMANY
[2] UNIV CRACOW, SCH MED, CHAIR SURG 1, KRAKOW, POLAND
关键词
D O I
10.1093/ije/22.4.606
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
A multicentre hospital-based incident case-control study with 520 male gastric cancer cases aged <75 years and an equal number of age- and sex-matched controls without cancer has been carried out in Poland to assess potential risks due to smoking and alcohol consumption. It was shown that after adjusting for socio-demographic and dietary confounders and vodka drinking, smoking cigarettes had no significant effect on risk. The estimated relative risk (RR) increased to 2.27 (95% confidence interval [Cl] : 0.97-5.28) for intestinal cardia cancer for those who smoked cigarettes without filters. The RR for stomach cancer grew as the frequency and amount of vodka drunk increased. People drinking vodka at least once a week had about a threefold higher risk compared to non-drinkers (RR = 3.06, 95% Cl : 1.90-4.95). The effect of vodka drinking on risk was particularly strong for non-cardia cancers of the intestinal type. Those who usually drank vodka before breakfast had an elevated risk (RR = 2.98, 95% Cl : 1.60-5.53) which was also present in all the subgroups investigated. Cardia and non-cardia cancer showed differences with respect to the interaction between tobacco smoking and vodka drinking. For cancers of the cardia region the risk was low for non-smokers or those who drank small amounts of vodka. The risk for cardia cancer increased considerably for smokers of cigarettes without filters and vodka drinkers who consumed large amounts (RR = 3.70, 95% Cl : 1.13-12.06). For the non-cardia region a uniform increase could be observed for vodka drinking regardless of cigarette smoking status. The findings of this study support the hypothesis that the effect of tobacco smoking and vodka drinking may be different for cardia cancer compared to the more distal cancers.
引用
收藏
页码:606 / 613
页数:8
相关论文
共 39 条
  • [1] CONSUMPTION OF ALCOHOL, COFFEE, AND TOBACCO, AND GASTRIC-CANCER IN SPAIN
    AGUDO, A
    GONZALEZ, CA
    MARCOS, G
    SANZ, M
    SAIGI, E
    VERGE, J
    BOLEDA, M
    ORTEGO, J
    [J]. CANCER CAUSES & CONTROL, 1992, 3 (02) : 137 - 143
  • [2] CANCER AND NONCANCER CONTROLS IN STUDIES ON THE EFFECT OF TOBACCO AND ALCOHOL-CONSUMPTION
    BARRA, S
    BARON, AE
    FRANCESCHI, S
    TALAMINI, R
    LAVECCHIA, C
    [J]. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 1991, 20 (04) : 845 - 851
  • [3] BLOT WJ, 1992, CANCER RES, V52, pS2119
  • [4] DIETARY RISK-FACTORS IN INTESTINAL AND DIFFUSE TYPES OF STOMACH-CANCER - A MULTICENTER CASE-CONTROL STUDY IN POLAND
    BOEING, H
    JEDRYCHOWSKI, W
    WAHRENDORF, J
    POPIELA, T
    TOBIASZADAMCZYK, B
    KULIG, A
    [J]. CANCER CAUSES & CONTROL, 1991, 2 (04) : 227 - 233
  • [6] Breslow N, 1980, STATISTICAL METHODS, V32
  • [7] A CASE-CONTROL STUDY OF GASTRIC-CANCER AND DIET IN ITALY .3. RISK PATTERNS BY HISTOLOGIC TYPE
    BUIATTI, E
    PALLI, D
    BIANCHI, S
    DECARLI, A
    AMADORI, D
    AVELLINI, C
    CIPRIANI, F
    COCCO, P
    GIACOSA, A
    LORENZINI, L
    MARUBINI, E
    PUNTONI, R
    SARAGONI, A
    FRAUMENI, JF
    BLOT, WJ
    [J]. INTERNATIONAL JOURNAL OF CANCER, 1991, 48 (03) : 369 - 374
  • [8] A CASE-CONTROL STUDY OF GASTRIC-CANCER AND DIET IN ITALY
    BUIATTI, E
    PALLI, D
    DECARLI, A
    AMADORI, D
    AVELLINI, C
    BIANCHI, S
    BISERNI, R
    CIPRIANI, F
    COCCO, P
    GIACOSA, A
    MARUBINI, E
    PUNTONI, R
    VINDIGNI, C
    FRAUMENI, J
    BLOT, W
    [J]. INTERNATIONAL JOURNAL OF CANCER, 1989, 44 (04) : 611 - 616
  • [9] GASTRIC SECRETION IN PATIENTS WITH CHRONIC PANCREATITIS AND IN CHRONIC ALCOHOLICS
    CHEY, WY
    KUSAKCIOGLU, O
    DINOSO, V
    LORBER, SH
    [J]. ARCHIVES OF INTERNAL MEDICINE, 1968, 122 (05) : 399 - +
  • [10] EFFECT OF CIGARETTE-SMOKING AND ALCOHOL-CONSUMPTION IN THE ETIOLOGY OF CANCERS OF THE DIGESTIVE-TRACT
    CHOI, SY
    KAHYO, H
    [J]. INTERNATIONAL JOURNAL OF CANCER, 1991, 49 (03) : 381 - 386