IMMUNOLOGICALLY ACTIVE POLYSACCHARIDE FROM CETRARIA-ISLANDICA

被引：37

作者：

INGOLFSDOTTIR, K ^{[1
]}

JURCIC, K ^{[1
]}

FISCHER, B ^{[1
]}

WAGNER, H ^{[1
]}

机构：

[1] UNIV MUNICH, INST PHARMAZEUT BIOL, D-80333 MUNICH, GERMANY

来源：

PLANTA MEDICA | 1994年 / 60卷 / 06期

关键词：

CETRARIA ISLANDICA; PARMELIACEAE; ICELAND MOSS; GALACTOMANNAN; PLANT POLYSACCHARIDE; IMMUNOLOGICAL ACTIVITY;

D O I：

10.1055/s-2006-959564

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new alkali-soluble polysaccharide has been isolated from Iceland moss, Cetraria islandica (L.) Ach., by ethanol fractionation, ion-exchange chromatography, and gel filtration. The mean M(r) was estimated to be 18,000. Sugar and methylation analysis, partial hydrolysis, and C-13-NMR spectroscopy showed the polysaccharide to be a branched galactomannan with a backbone composed of two structural elements; (1-->6)-linked alpha-D-mannopyranosyl and alpha-D-(1-->6)-galactopyranosyl units. The polysaccharide showed pronounced immunostimulating activity in an in vitro phagocytosis assay and in the in vivo carbon clearance assay.

引用

页码：527 / 531

页数：5

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