MYOCARDIAL KINETICS OF RADIOLABELED PERFUSION AGENTS - BASIS FOR PERFUSION IMAGING

被引：19

作者：

DAHLBERG, ST ^{[1
]}

LEPPO, JA ^{[1
]}

机构：

[1] UNIV MASSACHUSETTS, MED CTR, DIV CARDIOL, WORCESTER, MA 01655 USA

来源：

JOURNAL OF NUCLEAR CARDIOLOGY | 1994年 / 1卷 / 02期

关键词：

MYOCARDIAL PERFUSION IMAGING; CORONARY BLOOD FLOW; THALLIUM; 201; SESTAMIBI; TEBOROXIME; TETROFOSMINE;

D O I：

10.1007/BF02984091

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The myocardial deposition of radiolabeled perfusion agents permits the noninvasive assessment of regional coronary blood flow. The design of imaging protocols and the optimal interpretation of clinical perfusion studies are based on an understanding of the kinetics of blood-tissue exchange for these compounds. Thallium 201 and the technetium 99m-labeled compounds sestamibi, teboroxime, and tetrofosmin show differing myocardial extraction and retention. This review focuses on studies that used cell culture, isolated heart, and intact animal models that form the basis of our current understanding of the myocardial kinetics of these imaging agents.

引用

页码：189 / 197

页数：9

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