EARLY AGE AT 1ST BIRTH AND DECREASED RISK OF BREAST-CANCER

被引：33

作者：

BAIN, C

WILLETT, W

ROSNER, B

SPEIZER, FE

BELANGER, C

HENNEKENS, CH

机构：

[1] HARVARD UNIV, SCH MED, CHANNING LAB, DEPT MED, BOSTON, MA 02115 USA

[2] HARVARD UNIV, SCH MED, CHANNING LAB, DEPT SOCIAL & PREVENT MED, BOSTON, MA 02115 USA

[3] HARVARD UNIV, PETER BENT BRIGHAM HOSP, BOSTON, MA 02115 USA

[4] HARVARD UNIV, SCH PUBL HLTH, DEPT EPIDEMIOL, BOSTON, MA 02115 USA

来源：

AMERICAN JOURNAL OF EPIDEMIOLOGY | 1981年 / 114卷 / 05期

关键词：

D O I：

10.1093/oxfordjournals.aje.a113241

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The relationship between age at birth of a 1st child and breast cancer was evaluated for 1159 affected women and 11,590 women without cancer in data collected in 1976 among married female registered nurses residing in 11 states in the USA. A positive trend of increasing risk of breast cancer with later ages at 1st birth was found (.chi.12 for trend in populations = 30.9, P < 0.01). Adjustment for potential confounding variables by multiple logistic regression did not affect this trend. The presence of this relationship using non-hospitalized controls of similar social status to cases supports the reality of this association, which was recently challenged as an artifact due to inappropriate choice of hospitalized controls.

引用

页码：705 / 709

页数：5

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