INCREASED EFFECT OF APOMORPHINE ON HOMOVANILLIC-ACID IN RATS TERMINATED FROM CHRONIC HALOPERIDOL

被引:10
作者
SMITH, RC [1 ]
NARASIMHACHARI, N [1 ]
DAVIS, JM [1 ]
机构
[1] ILLINOIS STATE PSYCHIAT INST,CHICAGO,IL 60612
关键词
D O I
10.1007/BF01675355
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Rats who where administered apomorphine seven days after termination of chronic treatment with haloperidol had significantly (59%) lower level of brain HVA than saline control rats. This finding is consistent with the behavioral evidence suggesting supersensitivity of post-synaptic dopamine receptors after termination of chronic haloperidol. © 1978 Springer-Verlag.
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页码:159 / 162
页数:4
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