EFFECTS OF PARAQUAT TREATMENT ON FISH TRANSAMINASE MOLECULAR SUBFORMS

被引：2

作者：

DEER, KA

NEMCSOK, J

BOROSS, L

SZAJANI, B

机构：

[1] Department of Biochemistry, Attila József University, Szeged, H-6701

来源：

FISH PHYSIOLOGY AND BIOCHEMISTRY | 1990年 / 8卷 / 01期

关键词：

carp; heart; liver; paraquat; silver carp; tissue necrosis; transaminase; wels;

D O I：

10.1007/BF00004434

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effects of paraquat (PQ; 1,1′-dimethyl-4,4′-bipyridylium dichloride) treatment were investigated in carp, silver carp and wels. The serum glutamic-oxalacetic transaminase (GOT; L-aspartate: 2-oxoglutarate aminotransferase, EC 2.6.1.1.) level was enhanced by 50% at 1 ppm exposure and by 100% at 10 ppm exposure in all species, and there was a change in the distribution of the molecular subforms of GOT in the liver and heart. The activities of the individual subforms decreased with increasing PQ concentration or after a longer exposure. In some cases, one of the subforms was no longer present in the liver. An increased serum GOT activity, a decreased enzyme activity in different organs and the disappearance of molecular subform indicate tissue damage. © 1990 Kugler Publications.

引用

页码：79 / 83

页数：5

共 23 条

[1] DISTRIBUTION OF TRANSAMINASES (AMINOTRANSFERASES) IN TISSUES OF PACIFIC SALMON (ONCORHYNCHUS) WITH EMPHASIS ON PROPERTIES AND DIAGNOSTIC USE OF GLUTAMIC-OXALACETIC TRANSAMINASE [J].