DETECTION OF SOMATOTROPIN RECEPTORS ON HUMAN MONOCYTES

被引：11

作者：

JAFARI, P

KHANSARI, DN

机构：

[1] N DAKOTA STATE UNIV,DEPT VET SCI MICROBIOL,FARGO,ND 58105

[2] IMMUNOBIOL LABS INC,NEW YORK,NY

来源：

IMMUNOLOGY LETTERS | 1990年 / 24卷 / 03期

关键词：

Growth hormone; Monocyte; Receptor; Somatotropin;

D O I：

10.1016/0165-2478(90)90048-U

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The expression of somatotropin receptors on human peripheral blood monocytes was investigated. Binding of [125] somatotropin to human monocytes was found to be specific and saturable. The binding was rapid and time-dependent, and was abolished by pretreatment of monocytes with trypsin. Scatchard plot analysis revealed that each cell bore more than 8×103 binding sites with an affinity constant of 1×108 M-1. © 1990.

引用

页码：199 / 202

页数：4

共 21 条

[1] SPECIFIC BINDING OF GROWTH-HORMONE TO THYMOCYTES
ARRENBRECHT, S
[J]. NATURE, 1974, 252 (5480) : 255 - 257
[2] OXYGEN-DEPENDENT MICROBIAL KILLING BY PHAGOCYTES .1.
BABIOR, BM
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1978, 298 (12) : 659 - 668
[3] INDUCTION OF SOMATOGENIC RECEPTORS IN LIVERS OF HYPERSOMATOTROPIC RATS
BAXTER, RC
ZALTSMAN, Z
TURTLE, JR
[J]. ENDOCRINOLOGY, 1982, 111 (03) : 1020 - 1022
[4] IDENTITY OF TUMOR NECROSIS FACTOR AND THE MACROPHAGE-SECRETED FACTOR CACHECTIN
BEUTLER, B
GREENWALD, D
HULMES, JD
CHANG, M
PAN, YCE
MATHISON, J
ULEVITCH, R
CERAMI, A
[J]. NATURE, 1985, 316 (6028) : 552 - 554
[5] ROLE OF GROWTH-HORMONE IN REGULATING T-DEPENDENT IMMUNE EVENTS IN AGED, NUDE, AND TRANSGENIC RODENTS
DAVILA, DR
BRIEF, S
SIMON, J
HAMMER, RE
BRINSTER, RL
KELLEY, KW
[J]. JOURNAL OF NEUROSCIENCE RESEARCH, 1987, 18 (01) : 108 - 116
[6] EDEN S, 1983, 14TH ACT END C STOCK, P39
[7] A NEWLY DEFINED PROPERTY OF SOMATOTROPIN - PRIMING OF MACROPHAGES FOR PRODUCTION OF SUPEROXIDE ANION
EDWARDS, CK
GHIASUDDIN, SM
SCHEPPER, JM
YUNGER, LM
KELLEY, KW
[J]. SCIENCE, 1988, 239 (4841) : 769 - 771
[8] GIRI JG, 1985, J IMMUNOL, V134, P343
[9] GOFF BL, 1987, CLIN EXP IMMUNOL, V68, P580
[10] INTERLEUKIN-1 INDUCTION BY LIPOPOLYSACCHARIDES - STRUCTURAL REQUIREMENTS OF THE 3-DEOXY-D-MANNO-2-OCTULOSONIC ACID (KDO)
HAEFFNERCAVAILLON, N
CAROFF, M
CAVAILLON, JM
[J]. MOLECULAR IMMUNOLOGY, 1989, 26 (05) : 485 - 494

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