GLYCOSAMINOGLYCANS AND EUKARYOTIC CELL CONTROL

被引:6
作者
CHIARUGI, VP [1 ]
VANNUCCHI, S [1 ]
DELROSSO, M [1 ]
CAPPELLETTI, R [1 ]
FIBBI, G [1 ]
CELLA, C [1 ]
TUPPER, J [1 ]
机构
[1] SYRACUSE UNIV, DEPT CELL BIOL, SYRACUSE, NY 13210 USA
关键词
D O I
10.1080/00087114.1979.10796779
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The molecular properties of [animal] cell surface glycosaminoglycans are considered as well as their interactions with other surface associated macromolecules including collagen, actomyosin and fibronectin. Experimental evidence are provided on the role of Ca ions in the modulation of cellular physiology at the cell coat level together with preliminary results suggesting the involvement of cell surface glycosaminoglycans in maturation and in neoplastic transformation of bone marrow leukocytes. The possible involvement of cell surface glycosaminoglycans in cellular recognition is postulated, and models are presented for a direct or a protein-mediated interaction at the cell surface level.
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页码:89 / 115
页数:27
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