PERSISTENT UPTAKE OF INDIUM-111-ANTIMYOSIN MONOCLONAL-ANTIBODY IN PATIENTS WITH MYOCARDIAL-INFARCTION

被引：16

作者：

MATSUMORI, A

YAMADA, T

TAMAKI, N

KAWAI, C

WATANABE, Y

YONEKURA, Y

ENDO, K

KONISHI, J

YOSHIDA, A

TAMAKI, S

机构：

[1] KYOTO UNIV,FAC MED,DEPT INTERNAL MED,DIV 3,54 KAWARACHO,SAKYO KU,KYOTO 606,JAPAN

[2] MITSUBISHI KYOTO HOSP,KYOTO,JAPAN

[3] KYOTO UNIV,FAC MED,DEPT NUCL MED,KYOTO 606,JAPAN

[4] TAKEDA HOSP,KYOTO,JAPAN

来源：

AMERICAN HEART JOURNAL | 1990年 / 120卷 / 05期

关键词：

D O I：

10.1016/0002-8703(90)90113-C

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Indium-111(111In)-antimyosin scintigraphy was investigated in 27 patients with myocardial infarction. 111In-antimyosin Fab was administered intravenously, and planar and single photon emission computed tomographic images were obtained 48 hours later. Uptake of 111In-antimyosin was present in 9 of 10 patients (90%) studied within 6 days of infarction. During the second week positive scans were seen in 16 of 16 patients (100%) including 13 (81%) who had normal creatine kinase levels. The mechanism of persistent positive antimyosin images in the subacute stage of myocardial infarction remains to be clarified. 111In-antimyosin scintigraphy may be useful as a noninvasive method for the detection of myocardial injury late and early after a suspected acute myocardial infarction. © 1990.

引用

收藏

页码：1026 / 1030

页数：5

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