CLONING AND SEQUENCING OF AN HSP70 GENE OF SCHISTOSOMA-MANSONI

被引：30

作者：

NEUMANN, S ^{[1
]}

ZIV, E ^{[1
]}

LANTNER, F ^{[1
]}

SCHECHTER, I ^{[1
]}

机构：

[1] WEIZMANN INST SCI,DEPT CHEM IMMUNOL,IL-76100 REHOVOT,ISRAEL

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 1992年 / 56卷 / 02期

关键词：

SCHISTOSOMA-MANSONI; HSP70; GENE; PROMOTER; HEAT SHOCK ELEMENT;

D O I：

10.1016/0166-6851(92)90188-P

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Schistosomes have a complex life cycle (vertebrate and molluscan hosts as well as larvae living freely in water) in which they are exposed to different environments and temperatures (20-degrees-C-37-degrees-C). Since heat shock genes are activated in response to stress and during development [1], it is of interest to study the hsp70 gene family in schistosome. To approach this issue we have isolated from Schistosoma mansoni a genomic clone containing the complete coding region of hsp70 and the 5' flanking DNA with transcription regulatory elements including HSE (heat shock element) sequences.

引用

页码：357 / 360

页数：4

共 10 条

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