TOXICOLOGICAL DRUG SCREENING BY THIN-LAYER CHROMATOGRAPHY

被引：10

作者：

OJANPERA, I

机构：

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 1992年 / 11卷 / 06期

关键词：

D O I：

10.1016/0165-9936(92)80047-A

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Toxicological drug screening by thin-layer chromatography is just turning into an instrumental technique, providing new challenges and possibilities for all stages of the process. In this article computerized system evaluation, automated sample application, instrumental modes of development, and computerized identification with R(F) values, colour reactions and spectra are reviewed. Yet TLC drug screening can be practised in an efficient and scientifically stimulating way without expensive apparatus.

引用

收藏

页码：222 / R15

相关论文

共 55 条

[1]

Ardrey RE, 1985, GAS CHROMATOGRAPHIC

[2]

BASELT RC, 1981, INTRO FORENSIC TOXIC, P199

[3] INFLUENCE OF THE BIOLOGICAL MATRIX ON RETENTION BEHAVIOR IN THIN-LAYER CHROMATOGRAPHY - EVIDENCE OF SYSTEMATIC DIFFERENCES BETWEEN PURE AND EXTRACTED DRUGS [J].

BOGUSZ, M ;

GIERZ, J ;

DEZEEUW, RA ;

FRANKE, JP .

JOURNAL OF CHROMATOGRAPHY, 1985, 342 (01) :241-244

[4] IMPACT OF BIOLOGICAL MATRIX AND ISOLATION METHODS ON DETECTABILITY AND INTERLABORATORY VARIATIONS OF TLC RF-VALUES IN SYSTEMATIC TOXICOLOGICAL ANALYSIS [J].

BOGUSZ, M ;

KLYS, M ;

WIJSBEEK, J ;

FRANKE, JP ;

DEZEEUW, RA .

JOURNAL OF ANALYTICAL TOXICOLOGY, 1984, 8 (04) :149-154

[5] INFLUENCE OF BIOLOGICAL MATRIX ON RETENTION BEHAVIOR AND IDENTIFICATION POSSIBILITIES OF SELECTED NEUTRAL AND ACIDIC DRUGS IN THIN-LAYER CHROMATOGRAPHY - AN INTERLABORATORY INVESTIGATION [J].

BOGUSZ, M ;

FRANKE, JP ;

WIJSBEEK, J ;

DEZEEUW, RA .

JOURNAL OF ANALYTICAL TOXICOLOGY, 1986, 10 (06) :245-249

[6]

BUSCH KL, 1991, HDB THIN LAYER CHROM, P183

[7] SOLID-PHASE EXTRACTION FOR THE SCREENING OF ACIDIC, NEUTRAL AND BASIC DRUGS IN PLASMA USING A SINGLE-COLUMN PROCEDURE ON BOND ELUT CERTIFY [J].

CHEN, XO ;

WIJSBEEK, J ;

VANVEEN, J ;

FRANKE, JP ;

DEZEEUW, RA .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1990, 529 (01) :161-166

[8] DRUG-SCREENING IN URINE BY TLC WITH SPECIAL REGARD TO REAGENTS WITH LOW TOXICITY [J].

DALDRUP, T ;

RICKERT, A .

FRESENIUS ZEITSCHRIFT FUR ANALYTISCHE CHEMIE, 1989, 334 (04) :349-353

[9] MODERN CHROMATOGRAPHIC PROCEDURES IN SYSTEMATIC TOXICOLOGICAL ANALYSIS [J].

DEZEEUW, RA .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1989, 488 (01) :199-213

[10]

EBEL S, 1990, JPC-J PLANAR CHROMAT, V3, P42

← 1 2 3 4 5 6 →